CYP2C9 enzyme

Celecoxib and the enzyme CYP2C9

Celecoxib is processed to a large extent by the enzyme CYP2C9. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of celecoxib can also differ from person to person, as can the risk of side effects.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with celecoxib.

Flurbiprofen and the enzyme CYP2C9

Flurbiprofen is processed to a large extent by the enzyme CYP2C9. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of flurbiprofen can also differ from person to person, as can the risk of side effects.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to flurbiprofen.

Ibuprofen and the enzyme CYP2C9

Ibuprofen is processed to a large extent by the enzyme CYP2C9 (and to a lesser extent by the enzymes CYP2C8, CYP2C19 en CYP3A4). The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of ibuprofen can also differ from person to person, as can the risk of side effects.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to ibuprofen.

In addition to your genetic predisposition, (non-genetic) hypersensitivity reactions can occur in rare cases. This is called NSAID intolerance.

Lornoxicam and the enzyme CYP2C9

Lornoxicam is processed to a large extent by the enzyme CYP2C9. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of lornoxicam can also differ from person to person, as can the risk of side effects.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with lornoxicam.

Meloxicam and the enzyme CYP2C9

Meloxicam is processed to a large extent by the enzyme CYP2C9. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of meloxicam can also differ from person to person, as can the risk of side effects.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with meloxicam.

Phenytoin and the enzyme CYP2C9

Phenytoin is processed to a large extent by the enzyme CYP2C9. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of phenytoin can also differ from person to person.
Mutations in the HLA-B*1502 gene may also be responsible for a hypersensitivity reaction to treatment with phenytoin.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with phenytoin.

Piroxicam and the enzyme CYP2C9

Piroxicam is processed to a large extent by the enzyme CYP2C9. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of piroxicam can also differ from person to person, as can the risk of side effects.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with piroxicam.

Tenoxicam and the enzyme CYP2C9

Tenoxicam is processed to a large extent by the enzyme CYP2C9. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of tenoxicam can also differ from person to person, as can the risk of side effects.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with tenoxicam.