Flucytosine and the enzyme DPD
A small proportion of flucytosine is converted to fluorouracil within the body. Fluorouracil is processed primarily by the enzyme DPD. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of flucytosine can also differ from person to person.
Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with flucytosine.
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